Siggi Clavien Discovers if Fasting Boosts Brainpower.

Siggi Clavien
3 min readJul 17, 2020


Fasting & the Brain — by Siggi Clavien

Siggi Clavien explores if hunger promotes new brain cells

Could fasting increase your brainpower? This is what Siggi Clavien, who is interested in anything related to health and detox, wanted to explore. A stomach hormonal agent that stimulates cravings seems to promote the growth of new mind cells and secure them from the impacts of aging, and might discuss why some people state that fasting makes them feel mentally sharper.

When ghrelin was first discovered, it came to be known as the hormonal hunger agent. Ghrelin is created by the stomach when it gets empty, and when we don’t eat for a few hours, the levels increase in our blood.

However, there is, likewise, proof that ghrelin can enhance cognition. Animals with reduced-calorie diets have better mental abilities, and ghrelin might be part of the reason. Infusing the hormone into mice boosts their efficiency in learning and memory tests, and appears to increase the number of neuron connections in their minds.

Jeffrey Davies at Swansea University, UK, discovered further evidence that ghrelin can stimulate mind cells to split and multiply, a procedure called neurogenesis. When they added the hormonal agent to mouse brain cells grown in a dish, it turned on a gene understood to cause neurogenesis, called a fibroblast growth factor.

How ghrelin affects the memory

If the same result happens in animals, this could be just how ghrelin applies its impacts on memory, Davies states. Young brain cells seem to enhance the ability to create new memories. This is because they are more sensitive, so they are more likely to be turned on by new settings. “These neurons will fire more easily than old neurons, and they set in play a new memory,” says Davies.

And there’s even more: Calorie restriction diet expands life of monkeys by years

The job might likewise have effects on dealing with neurodegenerative problems, such as Parkinson’s disease, which is triggered by a loss of a kind of brain cell. Previous research, consisting of some by Davies’s team, has discovered that ghrelin can aid protect pets from establishing a type of Parkinson’s illness.

In additional experiments, Davies’s team found that ghrelin protects brain cells in a dish from dying when they are motivated to simulate Parkinson’s condition. And Davies’s coworker Amanda Hornsby found that, in a research of 28 volunteers, individuals with Parkinson’s mental dementia, cognitive impairment triggered by Parkinson’s disease, have lower levels of ghrelin in their blood than people who don’t have the condition.

This supports that ghrelin, or various other chemicals that act the same way, could be used as a treatment for Parkinson’s mental deterioration, states Hornsby.

Siggi Clavien’s findings on recurring fasting

In individuals, following a diet of 25 percent fewer calories than the everyday recommended amount has several benefits to health, such as much better control of blood glucose levels. Some who try it have stated it additionally enhances their cognitive capabilities, although this is controversial — some studies have actually suggested it impairs individuals’s brainpower.

Trying to harness some of the health and wellness benefits of a calorie-restricted diet, some individuals are looking to intermittent fasting. It’s most likely, as an example, that the 5–2 diet, where people consume normally for 5 days, yet stay with 500 calories a day for the various other two, elevates ghrelin degrees.

Yet Nicolas Kunath of the Technical University of Munich, Germany, points out that brand-new brain cells take a few days to weeks to work. So people shouldn’t anticipate fasting to create instant results on their mental ability in this way.



Siggi Clavien

Siggi Clavien is a UK, London, based entrepreneur with a passion for health and detox.